Risk factors for implant-related complications in congenital early-onset scoliosis patients treated with traditional dual growing rods

English Keywords:Congenital early-onset scoliosis  Traditional dual growing rods  Implant-related complications  Risk factors  Logistic regression analysis

English Abstract:

  【Abstract】 Objectives: To identify risk factors for implant-related complications(IRCs) in congenital early-onset scoliosis(CEOS) patients treated with traditional dual growing rods(TDGR). Methods: Data of CEOS patients treated with TDGR were retrospectively reviewed. All patients received more than 2 lengthening procedures with a minimum of 2-year follow-up. Patients were divided into complication group and non-complication group. Clinical data of all patients, including age, number of lengthening procedures, lengthening intervals, duration of follow-up, implant-related complications, and radiographic measurements were collected. The univariate analysis and multivariate logistic regression analysis were performed to identify the risk factors associated with IRCs. Results: Among the 48 patients enrolled, 23 (47.9%) patients suffered 49 IRCs, including 15 cases of hook dislodgement, 12 cases of screw dislodgement, 8 cases of rod breakage, 2 cases of cap loosing, 12 cases of proximal junctional kyphosis. The univariate Logistic regression analysis revealed preoperative T5-12 kyphosis ≥40° and T10-L2 kyphosis ≥10° were significant risk factors (P<0.05). Multivariable Logistic regression analysis demonstrated that preoperative T10-L2 kyphosis ≥10° [OR 4.12, 95%CI (1.20-14.14), P=0.025] was independent risk factor of IRCs. Conclusions: Preoperative T10-L2 kyphosis ≥10° is independent risk factor for IRCs. Identification and proper correction of relevant spinal deformity may reduce IRCs incidence.