The risk factors of postoperative infection in spinal surgery

English Keywords:Spinal operation  Surgical site infection  Risk factors  Logistics analysis

English Abstract:

  【Abstract】 Objectives: To analyze the risk factors of postoperative infection in spinal surgery, and to explore how to control it. Methods: Patients who accepted spinal open surgery between January 1995 and December 2015 were reviewed, Chi-square test was used to analyze the related influencing factors(age, BMI, smoke, diabetes, other parts of infection, steroid hormones, operation time, cerebrospinal fluid leakage, second operation, internal fixation, posterior approach) of postoperative infection in spinal surgery, multiple Logistic regressions were used to analyze the positive risk factors. Results: All of 3964 patients with spinal open surgery were reviewed, among whom 36 cases including 9 males and 27 females were diagnosed with postoperative infection, age ranged from 16 years to 76 years, the average age was 61.2±3.6 years. Among them, 12 patients were diagnosed with diabetes, 3 patients were diagnosed with chronic infection, one patient had a history of taking steroid hormone drugs. The results of chi-square test showed that elder age, diabetes, obesity, long operation time, instrumentation, blood transfusion might increase the risk of spinal surgical infection, but not long-term smoking, steroids use, other parts of infection, cerebrospinal fluid leakage, second surgery, posterior surgery did not. Multiple Logistic regressions results showed that obesity, elder age, diabetes, instrumentation, blood transfusion and long operation time might increase the risk the spinal surgical infection, and the highest risk factors were obesity, blood transfusion and long operation time. Conclusions: Obesity, elder age, diabetes, instrumentation, blood transfusion and long operation time may increase the risk of spinal surgical infection. Related risk factors should be controlled to reduce the incidence of spinal surgical infection.