Risk factors for early lower extremity deep venous thrombosis after posterior lumbar interbody fusion

English Keywords:Posterior lumbar interbody fusion  Early  Lower extremity deep venous thrombosis  Risk factors

English Abstract:

  【Abstract】 Objectives: To investigate and analyze the risk factors of early lower extremity deep vein thrombosis after posterior lumbar interbody fusion. Methods: A total of 165 patients undergoing spinal fusion surgery in the Guangxi Zhuang Autonomous Region People′s Hospital from July 2015 to May 2017 were collected. Type-B ultrasonic was perforemed on lower extremities before and after surgery. According to the results of ultrasonography after surgery, these cases were divided into two groups, DVT group and non DVT group. Age, gender, BMI, diabetes, hypertension, blood clotting function, D-dimer, fusion segments, operation time, blood transfusion, anticoagulants, postoperative bed time were recorded. Chi square test was used to analyze the risk factors of early deep vein thrombosis after posterior lumbar interbody fusion, and multivariate logistic regression analysis was applied to explore the main risk factors of DVT. Results: The incidence of DVT after posterior lumbar interbody fusion was 14.5%(24 of 165 cases). Single-factor analysis showed that there were significant differences between the two groups in age, body mass index(BMI), operation time, blood transfusion and postoperative bed time. Multivariate logistic regression analysis showed age≥60(OR=6.444, 95% CI=2.116-19.628), BMI≥24kg/m2(OR=4.463, 95% CI=1.603-12.426), blood transfusion(OR=3.484, 95% CI=1.110-10.932), postoperative bed time≥5 days(OR=3.155, 95% CI=1.027-9.695) were risk factors associated with occurrence of DVT after posterior lumbar interbody fusion. Conclusions: Aged≥60, BMI≥24kg/m2, blood transfusion and postoperative bed time ≥5 days are more likely to have early lower extremity deep vein thrombosis after posterior lumbar interbody fusion.