Changes of diffusion coefficient values on lumbar vertebra for adolescent idiopathic thoracolumbar scoliosis with structural lumbar curve

English Keywords:Adolescent idiopathic scoliosis  Lumbar vertebra  Magnetic resonance imaging  Diffusion-weighted imaging

English Abstract:

  【Abstract】 Objectives: To compare apparent diffusion coefficient(ADC) values on the convex and concave side of lumbar vertebra in diffusion-weighted imaging(DWI) for adolescent idiopathic thoracolumbar scoliosis with structural lumbar curve. Methods: From June 2015 to June 2016, 30 females with adolescent idiopathic thoracolumbar scoliosis with structural lumbar curve were collected, and the ages were between 10 and 18, Cobb angles were from 40° to 60°. The ADC values of lumbar spine(L1-L5) were measured and compared on diffusion-weighted imaging in 30 patients with idiopathic scoliosis and 10 age-matched healthy control subjects. The ADC values of idiopathic scoliosis of concave side and convex side, the left and right sides in two groups were statistically analyzed. Results: According to the ADC values of lumbar vertebre in two groups, there was no significant difference of ADC between the two sides in lumbar segment(L1-L5) in control group(F=0.752, P=0.559; F=0.604, P=0.661). And significant difference was also not found in lumbar segment(L1-L5) in AIS group(F=1.268, P=0.301; F=1.250, P=0.291). The ADC values showed no significant difference between the right and left side in control group[(0.439±0.041)×10－3mm2/s vs (0.423±0.042)×10－3mm2/s, t=1.047, P=0.288]. The statistical difference between the concave side and convex side in AIS group was found[(0.391±0.012)×10－3mm2/s vs (0.553±0.037)×10－3mm2/s, P<0.01]. The mean ADC value of convex side was statistically higher than that of normal control, and the ADC value of concave side was statistically lower than that of normal control. And statistical correlation was not found between ADC values of curve apex vertebra and Cobb angle values(r=0.024, P=0.721). Conclusions: Significant difference of DWI parameter was showed between the two sides of lumbar vertebra in adolescent idiopathic thoracolumbar scoliosis.