Evaluation of dilute betadine immersion in reducing postoperative surgical site infection after spine surgery

English Keywords:Spine surgery  Surgery site infection  Betadine

English Abstract:

  【Abstract】 Objectives: To evaluate the role of intra-operative 1% dilute betadine solution immersion in prevention of surgical site infection(SSI) of spinal surgery. Methods: The study included 706 adult patients from January 2010 to December 2014 who underwent spine surgery by the same surgeon. The surgery such as vertebroplasty, debridement, Halo-Vest placement, percutaneous endoscopic spinal surgery, instrumentation removal were excluded. 1000-1500ml normal saline irrigation was used before wound closure in 319 patients from January 2010 to December 2012 as group 1. A two-minute 1% betadine solution immersion and a normal saline irrigation were used for the 387 patients from January 2013 to December 2014 as group 2. Results: 9 SSI occured in group 1(2.8%) including 2 superficial infections(0.6%) and 7 deep infections(2.3%). Only 1 superficial infection(0.2%) occured in group 2. The differences of total infection rate(P=0.009) and deep infection rate(P=0.009) between the two groups were statistically significant. Most variables between the two groups were comparable. Conclusions: Dilute betadine irrigation is an effective, simple and cheap way to reduce surgical site infection rate after spinal surgery. A higher-level and larger-scale study to explore the accurate efficacy and an optimal operation standard is still needed.