Analysis of refractures factors after percutaneous vertebroplasty

English Keywords:Percutaneous vertebroplasty  Relevant factor  Refractures

English Abstract:

  【Abstract】 Objectives: To investigate the associated risk factors of percutaneous vertebroplasty(PVP) for the treatment of osteoporotic vertebral compression fractures(OVCF) following fracture, and to investigate the main factor causing fracture. Methods: By retrospective analysis, 264 cases(394 vertebrae) patients of OVCF treated by PVP were divided into 34 cases as group A(refracture group), while the other 230 cases(no refracture group) were termed as group B. The follow-up time averaged 20.5±8.8 months(range 6-35 months), factors such as time, location and incidence rate of refracture, and patient′s age, gender, the number of vertebral cavity, QCT value, leakage of bone cement, VAS scores before and after operation, were recorded and analyzed. Results: Adjacent vertebral fracture and leaping vertebral fracture total rate of the first-refracture was 13%, the time was 11.7±9.2 months, 21 cases while the second and the third was occurred in 3 months.The rate of bone cement leakage was 9%, without clinical symptoms. Age, gender, the number of vertebral cavity was no significant differences in group A and B(P>0.05). There was significant difference of QCT value between group A and B(P<0.05). Compared with preoperation, significant difference of the VAS score appeared in 3 days postoperation of group A and B(P<0.05), there was significant difference of the VAS score in the final follow-up between two groups(P<0.05). A total of 34 cases(36 vertebral) had bone cement leakage, the rate was 9%, and no clinical symptoms appear after the leakage, leakage of bone cement was no significant differences in group A and B(P>0.05). Different parts of the bone cement leakage were compared between the two groups, there was no significant difference(P>0.05) whether intervertebral leakage or other parts of the leakage. There was no significant differences(P＞0.05) in VAS score(preoperation, postoperation, final follow-up) of patients with different parts of the bone cement leakage. Conclusions: There is satisfactory effect on patient with osteoporotic vertebral compression fractures treated by percutaneous vertebroplasty. Age, gender, the number of vertebral cavity, eakage of bone cement was no significant correlation of refracture after percutaneous vertebroplasty, a major factor of osteoporosis is likely to lead refracture after percutaneous vertebroplasty.