Influence of demographic factors and radiographic parameters on simplified Chinese version of SRS-22 patient questionnaire performance in adult idiopathic scoliosis

English Keywords:Adult idiopathic scoliosis  Quality of life  The simplified Chinese version of SRS-22 questionnaire  Influence factor

English Abstract:

  【Abstract】 Objectives: To investigate the influence of demographic factors and radiographic parameters on the simplified Chinese version of SRS-22 questionnaire in adult idiopathic scoliosis. Methods: From January 2008 to December 2012, 109 adult idiopathic scoliosis patients(17 males and 92 females) without a history of brace treatment or spine surgery completed the simplified Chinese version of SRS-22 questionnaire. The average age was 24.8 years(range, 19 to 40 years), and the average Cobb angle was 37.3°(range, 16° to 102°). Spearman correlation analysis was used to evaluate the correlation of SRS-22 domains with age, body mass index(BMI), Cobb angle and sagittal vertical axis(SVA). Comparisons were conducted in terms of SRS-22 subtotal scores and other domains with patient age(<30yrs vs. ≥30yrs), curve magnitude(<40° vs. ≥40°), curve pattern(thoracic vs. thoracolumbar/lumbar scoliosis) and gender. Results: Age was negatively correlated with SRS-22 subtotal scores, pain, mental status, function domain(r=-0.35, -0.50, -0.31 and -0.21, respectively. P<0.05). BMI was negatively correlated with pain domain(r=-0.23, P<0.05). Cobb angle was negatively correlated with SRS-22 subtotal scores, self-image and function domain(r=-0.31, -0.49, -0.30, respectively. P<0.05). SVA was negatively correlated with function domain(r=-0.26, P<0.05). Older adult patients had lower scores than younger adult patients in SRS-22 subtotal scores, pain and mental domain(P<0.05). Patients with large curve magnitude had lower SRS-22 subtotal scores, self-image and function domain than the patients with small curve magnitude(P<0.05). Patients with thoracic scoliosis had lower scores in self-image and mental domain compared with those with thoracolumbar/lumbar scoliosis(P<0.05). Female patients had lower pain domain score than male patients(P<0.05), but no difference was found in terms of other domains. Conclusions: Adult idiopathic scoliosis patients′ responses to SRS-22 questionnaire can be influenced by age, Cobb angle, BMI and sagittal balance. Patients with thoracic scoliosis present with poorer self-image and function than those with thoracolumbar/lumbar scoliosis. Female patients have lower tolerance of pain than male patients.