The primary clinical outcomes of lumbar interbody fusion with unilateral pedicle screw fixation

English Keywords:Ｕnilateral pedicle screw fixation  Ｌumbar disc herniation  Ｃlinical outcomes

English Abstract:

  【Abstract】 Objective：To explore the clinical outcomes of unilateral pedicle screw fixation compared with the classic bilateral fixation for the treatment of lumbar disc herniation.Method：Fifty-four patients with single-level lumbar disc herniation were randomized into 2 groups：group 1（n=32） with classic bilateral instrumentation，and group 2（n=22） with unilateral instrumentation.The demographic（sex，age and segment），pre- and post-operative data（operation time，blood loss，hospital day，average cost，ＶＡＳ　and ODI scores） of two groups were compared.Result：No significant difference was found in the demographic data of two groups.The pre-operative VAS of group 1 was 6.96 and ODI score was 41.88，while pre-operative VAS of group 2 was 7.23 and ODI score was 42.36.In the last follow-up，the VAS of group 1 declined to 2.91 and ODI score 18.75，while VAS of group 2 declined to 2.77 and ODI score 16.82.The follow-up data had statistical significance compared with pre-operative scores（Ｐ＜0.05），but no statistical significance between the two groups（Ｐ＞0.05）.Group 2 had shorter operation time（79.8min vs 102.2min），less blood loss（160.9ml vs 217.2ml） and lower cost （￥27444 vs ￥33451） compared with group 1.Conclusion：The unilateral fixation has the same effectiveness as bilateral fixation for the treatment of single-level lumbar disc herniation，and causes lower cost，shorter operative time and less blood loss.