Feature of bony structural parameters and their effect on degenerative lumbar scoliosis

English Keywords:Bony structural parameter  Intervertebral disc-endplate  Asymmetric degeneration  Lumbar scoliosis

English Abstract:

  【Abstract】 Objective：To investigate the relationship between intervertebral disc-endplate degeneration and bony structural parameterｓ and the effect of bony structural parameters on the development of degenerative lumbar scoliosis.Method：The imaging data of 120 patients with primary degenerative lumbar scoliosis in our hospital were retrospectively reviewed as case group，while 89 patients with lumbar degenerative disease and without lumbar scoliosis were selected as control group.The vertebral body and intervertebral height in both sides on frontal X-ray，and the facet joint orientation in both sides on CT scan were measured respectively.The average vertebral body height，average intervertebral disc height and average facet orientation were regarded as bony structural parameters.Lumbar scoliosis and lordosis Ｃobb′s angles of the case group were measured.The quantitative grading methods were used and the relationship between asymmetric bony structural parameters and intervertebral disc-endplate degeneration were analyzed through comparing bony structural parameters.Result：The bony structural parameters between convex and concave side of the case group showed significant difference（P＜0.05），which indicated asymmetric distribution of bony structural parameters in degenerative lumbar scoliosis，and the bony structural parameters between right and left side of the control group showed ｎｏ　significant difference（P＞0.05）.The degree of intervertebral disc-endplate degeneration between 2 groups showed significant difference（P＜0.05）.By correlation analysis，asymmetric degree of bony structural parameterｓ showed good correlation with degree of intervertebral disc-endplate degeneration（P＜0.05），which was positively correlated with lumbar scoliosis Ｃobb′s angle（0＜r＜1，P＜0.05），but negatively correlated with lumbar lordosis Ｃobb′s angle（-1＜r＜0，P＜0.05）.Linear regression existed between lumbar scoliosis angle as well as lordosis angle and asymmetric degree of bony structural parameterｓ（F=431.671　ａｎｄ　17.137，P＜0.01）.Conclusion：High degree of intervertebral disc-endplate degeneration is more often in degenerative lumbar scoliosis and bony structural parameters show asymmetric distribution which significantly correlate with asymmetric intervertebral disc-endplate degeneration.Lumbar scoliosis Ｃobb′s angle increaseｓ with progression of bony structural asymmetric degree，however lumbar lordosis Ｃobb′s angle decreaseｓ with ｉｔ.