Incidence and associated risk factors of new vertebral compression fractures following percutaneous vertebral augmentation

English Keywords:Percutaneous vertebral augmentation  New vertebral compression fractures  Osteoporosis

English Abstract:

  【Abstract】 Objective：To investigate the incidence and associated risk factors of new vertebral compression fractures（VCFs） following percutaneous vertebral augmentation.Method：150 patients undergoing percutaneous vertebral augmentation due to osteoporotic vertebral fractures from July 1，2007 to June 30，2009 were reviewed retrospectively.128 patients had no new compression fracture termed as group A，while the other 22 patients with new onset compression fracture were termed as group B.The patient age，gender，bone mineral density，number of preexisting VCFs，number of augmentation vertebral，location of preexisting VCFs，severity of prevalent vertebral fractures，average amount of bone cement injection，method of vertebral augmentation（PVP or PKP），cement leakage，site of new compression fractures，period between primary and subsequent VCFs were reviewed.Result：All 150 patients were followed up for at least 12 months.22 patients（14.7%） experienced new VCFs during the follow-up period.Of these，more preexisting VCFs and more augmented vertebrae were noted.The age，gender，bone mineral density，severity of prevalent vertebral fractures，average amount of bone cement injected and cement leakage showed no statistical difference between groups A and B.Patients receiving PVP had a higher incidence of new fractures compared with PKP.Conclusion：The number of preexisting VCFs and augmented vertebrae are risk factors associated with new onset compression fractures.Compared with PVP，patients undergoing PKP are more apt to develop new VCFs.