Correlative factors of adjacent vertebral fractures after percutaneous vertebroplasty for osteoporotic vertebral compression fractures

English Keywords:Percutaneous vertebroplasty  Vertebral fractures  Osteoporosis  Correlative factors

English Abstract:

  【Abstract】 Objective：To investigate the correlative factors of adjacent vertebral fractures after percutaneous vertebroplasty（PVP） for osteoporotic vertebral compression fractures（OVCFs）.Method：112 patients who underwent single level PVP for OVCFs from March 2004 to June 2008 were retrospectively reviewed.The correlative factors including age，sex，history of trauma，preoperative degree of vertebral compression，bone mineral density，surgical approach（unilateral or bilateral），analgesia means，presence of lumbar scoliosis，cement injection volume and intradisc cement leakage among patients who sustained adjacent vertebral compession fractures were analysed．Screening of single and multiple-factors Logistic regression analysis was used to determine independent factors.Result：21 of the 112 patients had new adjacent vertebral compression fractures after PVP in a total of 23 vertebraes，with the total rate of 18.8%.Univariate analysis showed that preoperative degree of vertebral compression，bone mineral density，cement injection volume and intradisc cement leakage were the variables associated with the onset of adjacent vertebral fractures（P<0．05）.In contrast，there was no significantly difference with regard to age，sex，history of trauma，operative approach，analgesia means，presence of lumbar scoliosis（P>0.05）.Multiple-factors Logistic regression analysis showed that the positive correlation between reoperative vertebral compression and the cement volume and intradisc leakage was one predominant corelative factor associated with adjacent vertebral fractures.Conclusion：Adjacent vertebral fractures after PVP for OVCFs may be associated with preoperative degree of vertebral compression，the cement injection volume of injected cement and intradisc cement leakage.