Application of ozone on autoimmunity of patients with lumbar prolapsed disc

English Keywords:Lumbar disc herniation  Medical ozone  Humoral immunity

English Abstract:

  【Abstract】　Objective：To investigate the use of ozone on autoimmunity of patients with lumbar prolapsed disc.Method：50 cases with lumbar prolapsed disc and 50 healthy adults were collected.The concentration levels of immunoglobulin G and M in peripheral blood by immunoturbidimetry between patients and healthy ones were compared，then lumbar disc herniation（LDH） patients underwent percutaneous intradiscal ozone-injection（PIOI），and the concentration levels of immunoglobulin G and M of these patients between pre-operation and post-operation were compared.Result：The immunoglobulin G and M level in peripheral blood of LDH patients were 16.04±2.58g/L and 1.79±0.45g/L respectively.Both were significantly higher than that of the healthy adults（13.33±2.67g/L and 0.89±0.34g/L）（P<0.01）.After operation，the levels were 14.15±2.43g/L and 1.43±0.39g/L for immunoglobulin G and M level respectively，both were significantly lower than those of preoperation（P<0.01）.Conclusion：Ozone for medical use can inhibit the auotoimmunity of patients with lumbar prolapsed disc，which remains one of the mechanisms for managing LDH.