Histological study of fascia lata on repairing intervertebral disc annulus

English Keywords:Lumbar intervertebrae disc  Fascia lata  Annulu  Repairing  Histology  Rabbit

English Abstract:

  【Abstract】 Objective：To investigate the feasibility of fascia lata on repairing intervertebral disc annulus.Method：16 healthy New Zealand rabbits were divided into 4 groups randomly.Intervertebral disc（L4/5） was exposed and removed by retroperitoneal approach in every rabbit.Then the artificial nucleus was implanted into disc cavity，and the incision of annulus was sewed by fascia lata.The animals were sacrificed at 4 weeks，8 weeks，12 weeks and 16 weeks after operation respectively，and the gross anatomical and histomorphology changes were studied.Result：All incisions of annulus were healed after operations.No protrusion of artificial nucleus was observed.4 weeks after operation，there was a thin layer of fibro granulation tissue developed on the surface of the fascia lata，and a few inflammatory cells were noted infiltrating into fascia lata.At 8 weeks，fibre granulation tissues developed much more than before，and more inflammatory cells could be observed， while no inflammatory cells were noted infiltrating into fascia lata.At 12 weeks，much more fibre granulation tissues blocked the surface of fascia lata.Inflammatory cells were evidenced and no inflammatory cells were noted infiltrating into fascia lata.At 16 weeks，fibre granulation tissues，fascia lata and annulus grew intersectionally，and no inflammatory cells were noted infiltrating into fascia lata，and fascia lata maintained the original structure with the fibra tissue orientated longitudinally and parallelly.Conclusion：Repairment of lumbar intervertebral disc annulu incision with fiscia lata is not apt to degradation，which can maintain its inherent structure as well as biomechanical properties.