带肌肉组织全颈椎三维有限元模型的建立及分析

The establishment and analysis of a three-dimensionalfinite element model of whole cervical spine with muscles

中文关键词:  颈椎  肌肉  有限元  生物力学

英文关键词:Cervical spine  Muscle  Finite element  Biomechanics

中文摘要:

  【摘要】 目的：建立带肌肉组织的全颈椎三维有限元模型并验证该模型的有效性，为进一步分析颈椎疾患的生物力学作用机制建立良好的工作平台。方法：选取一名34岁健康男性志愿者进行颈椎薄层CT扫描，将CT原始数据以Dicom格式存贮。用Mimics 17软件将CT图像逆向重建出颈椎三维点云模型，利用Geomagic Studio 2012软件把点云模型拟合成NURBS曲面模型，然后导入Hypermesh12软件中进行网格划分、赋予材料属性、定义接触及边界条件等操作，最后提交至ABAQUS 6.12软件进行有限元分析，将各个工况（前屈、后伸、侧弯和轴向旋转）下各节段活动度与文献数据进行比较，验证该模型有效性。结果：建立的带有肌肉组织的全颈椎三维有限元模型共包含789024单元，285045节点，外观与人体颈椎具有非常好的几何相似性。该模型在屈伸、侧弯及旋转工况下的活动度与文献数据进行了80次对比，共计24次（占30%）超出部分参考范围，其中，仅C5-6左右侧弯活动度8.4°、C0-C1左右旋转活动度24.2°超出所有参考范围（P＜0.05）。结论：本研究建立的带有肌肉组织的全颈椎三维有限元模型符合有限元分析几何相似性和力学相似性要求，可用于颈椎生物力学分析。

英文摘要:

  【Abstract】 Objectives: To establish a three-dimensional finite element model of whole cervical spine with muscles and evaluate its validity, in order to establish a good working platform for further analyzing the biomechanical mechanism of cervical spine diseases. Methods: A 34-year-old healthy male volunteer underwent cervical thin-section CT scans. The raw data of CT scans were stored in Dicom format. Then the CT data were reconstructed reversely with Mimics17 into the 3D cervical point cloud model which were further fitted into NURBS surface model with Geomagic Studio 2012. Then NURBS surface model was imported into Hypermesh12 for mesh partitioning, assignment of material property, definition of contact and boundary condition and other operations. Finally, finite element analysis was carried out with ABAQUS 6.12. The range of moves(ROMs) inflexion, extension, lateral bending and rotation were compared with the literature data in order to validate the model. Results: The model consisted of 789024 elements and 285045 nodes. In term of appearance, this model had good geometric similarity with the human cervical spine. The comparisons between the ROMs of the model in flexion, extension, lateral bending and rotation with the reference ranges provided by the literature data summed to 80 times, with 24 times(30%) exceeding a part of reference ranges and only C5-6 ROM in lateral bending(8.4°) and C0-C1 ROM in rotation(24.2°) exceeding all reference ranges(P＜0.05). Conclusions: The normal three-dimensional finite element model of whole cervical spine with muscles meets the standard of geometric and mechanical similarity required in finite element analysis, thuscan be used for the biomechanical analysis of cervical spine.