雷 宇,于 淼,刘晓光,曾 琳.脊髓型颈椎病患者脊髓MRI T2WI高信号的危险因素[J].中国脊柱脊髓杂志,2016,(7):585-590. |
脊髓型颈椎病患者脊髓MRI T2WI高信号的危险因素 |
中文关键词: 脊髓型颈椎病 MRI 高信号 |
中文摘要: |
【摘要】 目的:探讨脊髓型颈椎病(CSM)患者脊髓MRI T2WI高信号的危险因素。方法:2014年1月~2014年4月因CSM于我院骨科行手术治疗的185例患者被纳入研究。将脊髓MRI T2WI高信号分为3级:0级,无高信号;1级,T2WI有模糊而边界不清的高信号,且高信号范围局限于一个节段;2级,T2WI有明亮而边界清晰的高信号或高信号范围超过一个节段。在MRI T2WI横断位上测量脊髓压迫程度,在过伸、过屈位X线片上测量颈椎节段和整体活动度。对可能影响高信号的因素(性别、年龄、病程、术前mJOA评分、脊髓压迫程度、颈椎活动度、椎间盘退变程度)行单因素分析,挑选出有意义指标(P<0.1)行有序Logistic回归分析。结果:脊髓MRI T2WI高信号的发生率为72.4%。按照分级标准,0级51例(27.6%),1级86例(46.5%),2级48例(25.9%)。性别和脊髓压迫程度对高信号的影响有统计学意义(女性相对于男性的OR=0.366,脊髓压迫比值的OR=0.904,P<0.05),而年龄、病程、术前mJOA评分、椎间盘退变程度、颈椎活动度与高信号均无明显相关性(P>0.05)。结论:男性、脊髓压迫程度重为CSM患者脊髓MRI T2WI高信号的独立危险因素。 |
Risk factors of spinal cord increased signal intensity on T2-weighted magnetic resonance imaging in patients with cervical spondylotic myelopathy |
英文关键词:Cervical spondylotic myelopathy Magnetic resonance imaging Increased signal intensity Risk factor |
英文摘要: |
【Abstract】 Objectives: To investigate the risk factors affecting the spinal cord increased signal intensity(ISI) on T2-weighted magnetic resonance imaging(MRI) in patients with cervical spondylotic myelopathy(CSM). Methods: From January 2014 to April 2014, 185 patients with CSM in Peking University Third Hospital receiving surgery were included in this study. ISI were classified in three grades: grade 0, no ISI; grade 1, faint and fuzzy border, located in one disc level; grade 2, intense and well-defined border, extending more than one disc level. The degree of spinal compression was measured on the T2-weighted transverse MRI, both segmental and total range of motion(ROM) of cervical spine were measured on the flexion-extension X-Ray. The factors that might affect the progression of ISI were analyzed by single factor analysis first: gender, age, duration of symptoms, preoperative mJOA score, degree of spinal compression, degree of intervertebral disc degeneration, ROM of cervical spine. Then the meaningful factors(P<0.1) were picked out for ordinal Logistic regression analysis. Results: The incidence of ISI on T2-weighted MRI was 72.4%. According to the grading system: 51 cases in grade 0, accounting for 27.6%; 86 cases in grade 1, accounting for 46.5%; 48 cases in grade 2, accounting for 25.9%. The influence of gender and degree of spinal compression on ISI was statistically significant(female to male′s OR=0.366 and compression ratio′s OR=0.904, respectively, P<0.05), while there was no significant correlation among age, duration of symptoms, preoperative mJOA score, degree of intervertebral disc degeneration, ROM of cervical spine and ISI(P>0.05). Conclusions: Male and severe spinal compression were independent risk factors of spinal cord ISI on T2-weighted MRI in patients with CSM. |
投稿时间:2016-01-06 修订日期:2016-06-22 |
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