潘福敏,王善金,麻 彬,亓东铎,巴兆玉,黄宇峰,赵卫东,吴德升.Ⅱ型糖尿病与腰椎间盘退变的相关性[J].中国脊柱脊髓杂志,2015,(12):1079-1082. |
Ⅱ型糖尿病与腰椎间盘退变的相关性 |
中文关键词: 腰椎间盘退变 Ⅱ型糖尿病 磁共振 Pfirrmann分级 |
中文摘要: |
【摘要】 目的:探讨Ⅱ型糖尿病(DM)与腰椎间盘退变的相关性。方法:选择2013年因腰腿痛至我院脊柱外科门诊就诊并满足入选标准的390例50~60岁患者,详细记录患者DM病史,其中非DM患者123例(非DM组)、血糖控制较好患者140例(A组),血糖控制较差DM患者127例(B组);A组中DM≤10年68例(A1组),DM>10年72例(A2组);B组中DM≤10年60例(B1组),DM>10年67例(B2组)。用Pfirrmann评分系统对各组患者各节段腰椎间盘退变程度进行评分,用SPSS 19.0统计分析DM与腰椎间盘退变程度的相关性。结果:各组资料均服从正态分布(P>0.05)。各组间一般资料无显著性差异(P>0.05)。在L1/2~L5/S1每节段上,A1组Pfirrmann评分与非DM组无显著性差异(P>0.05);A2、B1及B2组的Pfirrmann评分显著高于非DM组(P<0.05)。A2、B2组Pfirrmann评分显著较A1、B1组高(P<0.05);B1、B2组Pfirrmann评分均较A1、A2组高(P<0.05)。在A、B组中,L1/2~L5/S1每一节段上腰椎间盘退变程度与DM病程呈显著性正相关(P<0.05)。结论:DM>10年及血糖控制不良是腰椎间盘退变的危险因素,腰椎间盘退变程度与DM病程呈正相关。 |
The relationship between type Ⅱ diabetes mellitus and lumbar disc degeneration |
英文关键词:Lumbar discs degeneration Diabetes mellitus Type Ⅱ Magnetic resonance imaging Pfirrmann grading system |
英文摘要: |
【Abstract】 Objectives: To observe the relationship between type Ⅱ diabetes mellitus(DM) and lumbar discs degeneration(LDD). Methods: During 2013, 390 adults with low back pain in our spine clinic were chosen according to the including criterion. All the patients were divided into the following three groups: non-DM group(n=123), well-controlled DM group(group A; n=140) and badly-controlled DM group(group B; n=127). In group A, 68 patients were with DM duration ≤10 years(group A1), and 72 patients with DM duration >10 years(group A2); in group B, there were 60 patients with DM duration ≤10 years(group B1) and 67 patients with DM duration >10 years(group B2). Severity of LDD was evaluated by the five-level Pfirrmann grading system. SPSS 19.0 was used to analyze the relationship between type Ⅱ DM and LDD. Results: The data of each group obeying the normal distribution(P>0.05) and demographic data showed no different between two groups(P>0.05). From L1/2 to L5/S1, the average Pfirrmann scores between group A1 and non-DM patients showed no difference(P>0.05); group A2, B1 and B2 showed higher average Pfirrmann scores than non-DM patients(P<0.05). Group A2 and B2 showed higher average Pfirrmann scores than group A1 and B1(P<0.05). Group B1 and B2 showed higher average Pfirrmann scores than group A1 and A2(P<0.05). From L1/2 to L5/S1, the severity of LDD was highly related to DM duration both in group A and B(P<0.05). Conclusions: DM duration >10 years and bad control of DM are the risk factors of LDD, and severity of LDD is highly related to DM duration. |
投稿时间:2015-05-26 修订日期:2015-10-29 |
DOI: |
基金项目:国家自然科学基金青年基金资助项目(编号:81201418);同济大学青年优秀人才培养行动计划资助项目(编号:2013KJ075);浦东新区卫生系统重点学科建设资助项目(编号:PWZx2014-02) |
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