基于Mimics软件计算椎体强化术后椎体内骨水泥体积及骨水泥/椎体体积比的新方法

A new method for calculating the volume of intravertebral bone cement and the ratio of intravertebral bone cement to vertebral body after vertebral augmentation based on Mimics software

中文关键词:  椎体强化术  骨水泥量  骨水泥/椎体体积比  Mimics软件

英文关键词:Mimics software  Bone cement quantity  Vertebral augmentation  The volume ratio of intravertebral bone cement to vertebral body

中文摘要:

  【摘要】 目的：建立基于Mimics软件计算椎体强化术后椎体内骨水泥量与骨水泥/椎体体积比的新方法，并验证其准确性与可靠性。方法：2012年1月～3月共有12例骨质疏松性椎体压缩骨折患者在我院接受椎体强化术（14个椎体），均使用标准化定量推注管道注入骨水泥，由2名脊柱外科医师准确记录骨水泥量，将他们记录的平均值定义为椎体内实际骨水泥量。术后对患者手术节段进行CT薄层扫描，再将CT数据输入Mimics软件，利用Mimics软件计算测量注入椎体的骨水泥量及椎体体积，并计算出椎体内骨水泥/椎体的体积比，将2名检测者计算出的骨水泥量平均值定义为椎体内骨水泥估计量，将计算出的椎体内骨水泥估计量与椎体内实际骨水泥量进行对比分析，判断这一新方法的准确性。并对2名不同检测者按照同样操作流程测量出的骨水泥体积及椎体体积进行比较，以判断这一新方法的可靠性。结果：12例患者（14个椎体）手术均顺利完成，术中未见明显骨水泥渗漏，2名医师记录的椎体内实际骨水泥量为4.99±0.60ml，检测者A测量出的骨水泥体积和椎体体积分别为5.01±0.61ml、26.66±2.93ml，检测者B测量出的骨水泥体积和椎体体积分别为5.02±0.59ml、26.64±2.92ml，检测者A及B测量出骨水泥体积的平均值（椎体内骨水泥估计量）为5.02±0.60ml，椎体内骨水泥/椎体体积比为0.19±0.03（0.13～0.23）。椎体内骨水泥估计量与椎体内实际骨水泥量相比无显著性差异（P＞0.05），骨水泥估计量及椎体体积计算量在2名不同检测者之间也无显著性差异（P＞0.05）。结论：Mimics软件可精确计算椎体内骨水泥量，并测量出骨水泥/椎体体积比，这一方法具有较好的准确性及可靠性，有利于进一步开展椎体强化术骨水泥量的相关研究。

英文摘要:

  【Abstract】 Objectives: To establish the accuracy and reliability of a new method for calculating the volume of intravertebral bone cement and the ratio of intravertebral bone cement to vertebral body after vertebral augmentation based on the Mimics software. Methods: 12 consecutive patients suffering from osteoporosis vertebral compression fracture were included in this study from January to March of 2012. All cases underwent vertebral augmentation during which the bone cements were injected into vertebral body, and the volume of injected bone cement was recorded by 2 spine surgeons which was defined as the real volume of intravertebral bone cement. All patients underwent the thin layer scanning of CT(Computer-tomography) at diseased segment, and the DICOM data format of CT was imported into Mimics software. Based on the Mimics software, the volume of intravertebral bone cement and the volume ratio of intravertebral bone cement to vertebral body after vertebral augmentation were calculated by the 2 surgeons, respectively, the average volume calculated by the 2 surgeons was defined as the estimated volume of intravertebral bone cement. The real volume of intravertebral bone cement and the estimated volume of intravertebral bone cement were compared for evaluating the accuracy of this new method, and the volumes of intravertebral bone cement and vertebral body calculated by the 2 different surgeons were compared for evaluating the reliability of this new method. Results: 12 patients suffered from no significant bone cement leakage during operation. The real volume of intravertebal bone cement recorded by the 2 surgeons was 4.99±0.60ml. The volume of intravertebral bone cement from surgeon A was 5.01±0.61ml and 26.66±2.93ml, respectively, while the volume from surgeon B was 5.02±0.59ml and 26.64±2.92, respectively. The estimated average volume of intravertebral bone cement from the 2 surgeons was 5.02±0.60ml, and the volume ratio of intravertebral bone cement to vertebral body was 0.19±0.03(range, 0.13-0.23). There was no significant difference between the real volume of intravertebal bone cement and estimated volume of intravertebral bone cement(P＞0.05)， moreover, there was no significant difference in the estimated volumes of intravertebral bone cement and vertebral body between 2 surgeons(P＞0.05). Conclusions: The Mimics software can be used for calculating the intravertebral bone cement accurately and estimating the ratio of intravertebral bone cement to vertebral body, which is of accuracy and reliability, and can be used for the further study.