椎体成形术中椎体骨密度对骨水泥弥散体积的影响

Effect of vertebral bone mineral density on bone cement distribution volume in percutaneous vertebroplasty

中文关键词:  椎体成形术  骨密度  骨水泥  弥散体积  注射体积

英文关键词:Vertebroplasty  Vertebral bone density  bone cement  Diffusion volume  Injection volume

中文摘要:

  【摘要】　目的：探讨椎体成形术中椎体骨密度对骨水泥弥散体积的影响。方法：18例胸腰椎压缩骨折患者，术前均行骨折椎体双能Ｘ线骨密度仪测定，根据WHO骨质疏松症诊断标准分为骨密度正常组（A组）、骨密度减低组（B组）及骨质疏松组（C组），每组6例，采用经伤椎单侧椎弓根行椎体成形术，术中注入相同状态和批次骨水泥2.5ml，术后采用64排CT扫描椎体，计算骨水泥注射体积及弥散体积。结果：所有患者均顺利完成手术并均成功注2.5ml骨水泥，CT计算骨水泥注射体积：A组2.460±0.116cm3，B组2.450±0.038cm3，C组2.457±0.037cm3；骨水泥在椎体中弥散体积：A组为6.717±1.127cm3，B组为5.650±0.669cm3，C组为4.617±0.542cm3。三组骨水泥弥散体积均大于同组注射体积（P<0.01）；三组间骨水泥注射提及比较均无统计学差异（P＞0.05）。弥散体积比较均有统计学差异（P<0.05），A组弥散体积最大。结论：椎体成形术中骨水泥弥散体积大于骨水泥注射体积；椎体骨密度与椎体内骨水泥弥散体积密切相关，骨密度越高，弥散体积越大。

英文摘要:

  【Abstract】 Objective：To investigate the effect of vertebral bone mineral density on bone cement distribution volume in percutaneous vertebroplasty.Method：The vertebral bone mineral density（BMD） of patients with thoracolumbar vertebral compression fracture was measured preoperatively by dual energy X-ray absorptiometry. According to the diagnostic criteria of osteoporosis of the WHO，18 patients were selected and divided into three groups：normal BMD group（group A），low BMD group（group B） and osteoporosis group（group C），with each group of 6 cases.All patients underwent unilateral vertebral vertebroplasty，with 2.5ml bone cement injection for each patient.All patients experienced CT scan postoperatively，and the volume of bone cement diffusion was calculated.Result：2.5ml bone cement was injected into ｅａｃｈ　ｏｆ　ｔｈｅ patients successfully.The mean injection volume of bone cement in group A was 2.460±0.116cm3，2.450±0.038cm3 in group B，and 2.457±0.037cm3 in group C.The mean diffusion volume of bone cement in group A was 6.717±1.127cm3，5.650±0.669cm3 in group B，and 4.617±0.542cm3 in group C，with ｂｉｇｇｅｒ diffusion volume than the injection volume（P<0.01）.Meanwhile，the ｂｉｇｇｅｓｔ diffusion volume was noted in group A，and the ｓｍａｌｌｅｓｔ diffusion volume in group C， which showed significant difference（P<0.05）.Conclusion：The bone cement diffusion volume is ｂｉｇｇｅｒ　than injectｉｏｎ volume in vertebroplasty.The BMD of vertebral body is closely associated with the diffusion volume of bone cement.The higher BMD of the vertebral body，the ｂｉｇｇｅｒ diffusion ｖｏｌｕｍｅ　of bone cement.