影响经皮椎体后凸成形术椎体高度恢复的相关因素分析

Analysis of related factors on the vertebral height restoration of percutaneous kyphoplasty

中文关键词:  经皮椎体后凸成形术  椎体高度恢复  相关因素

英文关键词:Ｐercutaneous kyphoplasty  Ｖertebral height restoration  Ｃorrelative factor

中文摘要:

  【摘要】 目的：探讨影响经皮椎体后凸成形术治疗骨质疏松性椎体压缩骨折椎体高度恢复的相关因素。方法：对2007年1月~2008年10月于我院因骨质疏松性椎体压缩骨折行单节段经皮椎体后凸成形术的43例患者进行回顾性分析。分别记录患者的年龄、性别、病程、有无外伤史、术前椎体压缩程度、术前矢状面Cobb角、骨折类型、骨密度、手术入路途径、骨水泥剂量及有无侧凸畸形等相关因素，观察患者术后压缩椎体高度恢复情况，应用双变量回归分析及t检验行单因素分析，应用多元线性回归分析行多因素分析，研究各因素与经皮椎体后凸成形术椎体高度恢复情况的相互关系。结果：术后椎体高度恢复率为（39±17）%。单因素分析结果显示患者的病程、术前椎体压缩程度、骨折类型、骨密度及有无腰椎侧凸与术后椎体高度恢复情况有一定的相关性（P<0.05），而患者的年龄、性别、术前矢状面Cobb角、骨水泥剂量及手术途径与术后椎体高度恢复情况无相关性（P>0.05）。多因素分析结果显示患者术前椎体压缩程度、骨密度及骨折类型是影响术后椎体高度恢复情况的主要因素，其标准化偏回归系数分别为-0.622、-0.283、0.131。结论：患者术前椎体压缩程度、骨密度及骨折类型是影响经皮椎体后凸成形术椎体高度恢复的主要因素，观察患者的这些指标有助于预测经皮椎体后凸成形术椎体高度恢复情况。

英文摘要:

  【Abstract】 Objective：To explore the correlative factors on vertebral height restoration of percutaneous kyphoplasty（PKP） in the treatment of osteoporotic vertebral compression fracture.Method：Forty-three patients experiencing single level kyphoplasty due to osteoporotic vertebral compression fracture from January 2007 to October 2008 were retrospectively reviewed.The correlative factors including age，sex，course of disease，history of trauma，preoperative degree of vertebral compression，preoperative Cobb′s angle，fracture type，bone mineral density，operative approach，cement volume and existence of lumbar scoliosis were put into analysis.All the factors as well as the degree of vertebral height restoration were recorded.Bivariate linear regression analysis and t-test were uesd to find the most correlative factors affecting vertebral height restoration.And multiple linear regression analysis was uesd to find independent factors.Result：The whole degree of vertebral height restoration was （39±17）%.Univariate analysis showed that the course of disease，preoperative degree of vertebral compression，fracture type，bone mineral density and lumbar scoliosis were the variable associated with the vertebral height restoration（P<0.05）.In contrast，there was no significantly correlation between age，sex，preoperative Cobb′s angle，cement volume，operative approach and the vertebral height restoration（P>0.05）.Multiple linear regression analysis showed that the preoperative degree of vertebral compression，bone mineral density and fracture type were the predominant correlative factors affecting the vertebral height restoration.The standardized partial regression coefficient was -0.622，-0.283 and 0.131 respectively.Conclusion：The preoperative degree of vertebral compression，bone mineral density and fracture type are the predominant correlative factors affecting the vertebral height restoration which can be used to forecast the prognosis of percutaneous kyphoplasty.