颈椎软骨终板钙化与颈椎间盘退变和椎体骨赘形成的关系

Study on the relationship between the cartilage end-plate calcification and intervertebral disc degeneration and vertebral osteophyte formation in cervical vertebrae

中文关键词:  颈椎椎间盘退变 软骨终板钙化 骨赘

英文关键词:Cervical vertebrae,Intervertebral disc,Cartilage end-plate,Degeneration,Osteophyte

中文摘要:

  目的：研究颈椎软骨终板钙化与颈椎间盘退变和颈椎椎体骨赘形成的关系。方法：应用组织学方法观察颈前路环锯手术切下的18例脊髓型颈椎病和4例颈椎过伸性损伤致颈椎间盘突出患者的颈椎间盘及相邻的上下椎体标本，研究不同退变程度颈椎间盘软骨终板和椎间盘的形态学变化及椎体骨赘形成过程。结果：退变程度较轻或基本正常的颈椎间盘软骨终板结构良好，潮标清晰，退变程度较重的颈椎间盘软骨终板发生明显纤维化，潮标前移，钙化软骨和软骨下骨板增厚，退变颈椎间盘周边软骨终板潮标明显前移，钙化和骨化层增厚，形成突向外侧的椎体边缘的骨赘。结论：颈椎软骨终板的不断钙化和骨化导致颈椎间盘营养发生障碍可能是启动颈椎间盘退变的关键因素，退变椎体周边软骨终板的不断钙化和骨化是椎体骨赘形成的根本原因。

英文摘要:

  Objective:To study the relationship between the end-plate calcification and cervical intervertebral disc degeneration and vertebral osteophyte formation.Method:Histological method was applied to observe cervical interverbral discs with adjacent bilateral