脊髓损伤后疼痛病人与非疼痛病人分辨阈的测定

Tactual discrimination thresholds in spinal cord injured patients with and without pain

中文关键词:  脊髓损伤，疼痛，两点分辨觉，可塑性，躯体感觉皮层

英文关键词:Spinal cord injuries Pain Two-point discrimination threshold Plasticity Somatosensory cortex

中文摘要:

  设想脊髓损伤（ＳＣＩ）平面以下自发性感觉异常性疼痛综合症（ＤＰＳ）是由于ＳＣＩ后躯体感觉系统的失神经传入所致的躯体感觉皮层重组所引起。故对１６例有ＤＰＳ的ＳＣＩ病人，１５例无疼痛的ＳＣＩ病人和１６例健康人的前臂、颈部和脊柱皮肤区做了两点分辨阈（２ＰＤＴ）的检查。结果显示：疼痛组比非疼痛组及对照组有较低的２ＰＤＴ，尤其是在脊柱和颈部。ＳＣＩ疼痛组的脊柱皮肤区在ＤＰＳ疼痛强度和２ＰＤＴ之间呈明显的负相关，即疼痛强度越高，２ＰＤＴ就越低。研究结果支持ＤＰＳ起源于ＳＣＩ后大脑躯体感觉皮层重组的设想。

英文摘要:

  Spontaneous dysesthetic pain syndrome (DPS) below the level of spinal cord injury (SCI) is one of the most common complications of traumatic SCI.Authors hypothesized that DPS in SCI patients resulted form the reorganization of the somatosensory cortex due