颈椎病患者突出椎间盘周围的炎症反应及临床意义

Inflammation in the tissue adjacent to herniated cervical disc in patients with cervical spondylosis and its clinical meanings

中文关键词:  颈椎病 炎症 不稳定

英文关键词:Cervical spondylosis,Inflammation,Instability of cervical spine

中文摘要:

  目的：观察颈椎病患者突出椎间盘周同组织的病理表现，并探讨其临床意义。方法：79例颈椎病患者手术切除100个突出的椎间盘；取出间盘周围的绀织进行HE染色及免疫绀化染色。将染色结果结合其临床表现、影像学资料进行分析。结果：45个(45％)突出间盘周围的组织内可见血管增生、炎症细胞浸润：炎症组与无炎症组患者在病程、术后脊髓功能改善方面存在显著性差异；炎症反应与颈椎不稳定之间存在显著相关性。结论：(1)部分颈椎病患者突出椎间盘周围组织内存在慢性炎症反应，炎症浸润细胞多为单核-巨噬细胞及淋巴细胞；(2)颈椎不稳定可能是造成突出椎间盘周围组织内炎症反应的原因之一；(3)慢性炎症因素可能参与了颈椎病的发病。

英文摘要:

  Objective:To study the pathology of tissue adjacent to herniated cervical disc in patients with cervical spondylosis,and its clinical meanings.Method:79 patients were studied,and 100 discs and its adjacent tissue were obtained during operation.The 100 dis