陈立科,李康华,曹盛俊.几丁糖与人工骨联合应用预防椎板切除术后硬膜外粘连的实验研究[J].中国脊柱脊髓杂志,2005,(4):-241,i002.
几丁糖与人工骨联合应用预防椎板切除术后硬膜外粘连的实验研究
Prevention of epidural adhesion after laminectomy by the use of chitin combined with artificial bone
  
DOI:
中文关键词:  椎板切除术 硬膜 粘连 几丁糖 人工骨
英文关键词:Laminectomy,Dura mater,Adhesions,Chitin,Artificial bone
基金项目:
陈立科  李康华  曹盛俊
中南大学湘雅医院骨科 410008湖南省长沙市 (陈立科,李康华)
,中南大学湘雅医院骨科 410008湖南省长沙市(曹盛俊)
摘要点击次数: 3776
全文下载次数: 2880
中文摘要:
  目的:观察椎板切除术后用几丁糖(CHT)的同时在椎板缺损处植入磷酸三钙人工骨(TCP)预防硬膜外瘢痕粘连的效果。方法:40只纯种日本大耳白兔随机分成A、B、C、D四组,制作L4椎板损伤模型。A组硬膜外涂布生理盐水,B组硬膜外涂布几丁糖,C组硬膜外覆盖人工骨,D组硬膜外涂布几丁糖的同时加人工骨覆盖。术后12周对椎板切除部位进行大体观察、组织学观察及生化检查,比较各组间瘢痕形成和粘连情况。结果:B、C、D组的改良Rydell-Balazs粘连韧度评分、胶原含量及改良Nussvaum组织学评分均优于A组(P<0.01),D组优于B组与C组(P<0.05),B组与C组无显著性差异(P>0.05)。结论:联合应用几丁糖和人工骨能有效预防硬膜外瘢痕粘连的形成,比单独应用几丁糖和人工骨预防效果好。
英文摘要:
  Objective:To observe the effect of chitin cooperated with artificial bone(beta-tricalcium phosphate,TCP) in the prevention of fibrous scar formation in the epidural space after laminectomy.Method:40 rabbits were divided randomly into 4 groups.Laminectomy
查看全文  查看/发表评论  下载PDF阅读器
关闭
function PdfOpen(url){ var win="toolbar=no,location=no,directories=no,status=yes,menubar=yes,scrollbars=yes,resizable=yes"; window.open(url,"",win); } function openWin(url,w,h){ var win="toolbar=no,location=no,directories=no,status=no,menubar=no,scrollbars=yes,resizable=no,width=" + w + ",height=" + h; controlWindow=window.open(url,"",win); } &et=318DFCB05C203DB686AF0832A1D69468CA49D4056D642D4E451EBDF93D84B626A3A2D803645248022B6199C67E2A3CB5B160F011FABBECBA2FBED75D8429112F31C31C6EEEB0E1B884E3B65C8FC06CA8D410EB0B46179E1359A5FBB973454470D943C013EAF9EF78&pcid=A9DB1C13C87CE289EA38239A9433C9DC&cid=527A01A248DACB72&jid=9262A66F274A6CFEEBE23EC40CDE54FC&yid=2DD7160C83D0ACED&aid=8C458A67AB0B1896&vid=&iid=E158A972A605785F&sid=&eid=A128DA2621241A5214F4999DCF4FB5F6&fileno=20050492&flag=1&is_more=0"> var my_pcid="A9DB1C13C87CE289EA38239A9433C9DC"; var my_cid="527A01A248DACB72"; var my_jid="9262A66F274A6CFEEBE23EC40CDE54FC"; var my_yid="2DD7160C83D0ACED"; var my_aid="8C458A67AB0B1896";