李卫国,邱勇,$2,凌为其,朱丽华,朱泽章.脊柱节段血管阻断对椎间盘退变发生发展的影响[J].中国脊柱脊髓杂志,2004,(6):-351,i002.
脊柱节段血管阻断对椎间盘退变发生发展的影响
Effects of blocking the segmental vessels of the spine on the development of disc degeneration
  
DOI:
中文关键词:  椎间盘 退行性改变 节段血管 蛋白多糖 胶原
英文关键词:Intervertebral disc,Degeneration,Segmental vessels,Proteoglycan,Collagen
基金项目:
李卫国  邱勇  $2  凌为其  朱丽华  朱泽章
[1]南京大学医学院附属鼓楼医院脊柱外科,南京市210008 [2]常州市第一人民医院骨科,常州213003
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中文摘要:
  目的:探讨结扎脊柱节段血管对椎间盘退变发生发展的影响。方法:16只成年犬随机平均分为两组.每只犬均结扎左侧T6~T9的节段血管。分别于造模后3个月和8个月急性失血法各处死一组动物,处死后立即取整段胸椎。T6,7至T8/9为实验区(结扎节段血管区),取结扎血管以上的T4/5椎间盘为病理检查中的对照区,T6/7为病理检查实验区;T7/8和F8/9椎间盘为生化分析的实验区,结扎血管以下的T11/12、T12/13椎间盘为生化分析的对照区。对对照区和实验区内椎间盘的形态和成分进行比较。结果:与对照组相比.实验组的椎间盘在3个月时胶原成分已有显著增加,而糖胺多糖成分显著降低;8个月组与3个月组无显著性区别。结论:在脊柱节段血管阻断后,椎间盘的周围血供减少,影响椎间盘的营养供应,可诱发或加速椎间盘的退变。
英文摘要:
  Objective:To investigate the effects of blocking the segmental vessels of the spine on the development of disc degeneration.Method:Sixteen dogs were randomly divided into two groups.Under general anesthesia,the left segmental vessels from T6 to T9 of the
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